Heart: Kanna & Rose Gummies — 25 mg Kanna with Valerian | 10 ct

Kanna is native to the Cape region of South Africa, where the San and Khoikhoi peoples have used it for centuries. The traditional preparation, kougoed, involves crushing and fermenting the succulent, then chewing it — a process that appears to alter the alkaloid profile rather than merely drying the plant. Dutch colonial records from the seventeenth century describe it already being traded inland, which tells you something about how valued it was.

In its own tradition kanna is a plant of sociability and of easing what is held tight — used before gathering, before difficult conversation, before long walking.

Rose and valerian come from a different lineage. Rose appears across Persian, Ayurvedic, and European herbal traditions as a heart remedy in both the physical and emotional senses. Valerian (Valeriana officinalis) has been used in European herbalism since at least the classical period for settling the nerves.

Kanna's alkaloids are among the better-characterised in this category:

• Serotonin reuptake inhibition. Mesembrine, kanna's principal alkaloid, is a potent serotonin reuptake inhibitor in laboratory assays — the same broad mechanism class as a familiar family of pharmaceuticals, though studied at very different doses and contexts.
• PDE4 inhibition. Mesembrenone shows phosphodiesterase-4 inhibition, a separate pathway associated with intracellular signalling.
• Alkaloid profile. Mesembrine, mesembrenone, mesembrenol, and tortuosamine occur in varying ratios depending on plant chemotype and preparation — which is why traditional fermentation is more than a preservation step.
• Valerenic acid, from valerian, has been studied as a GABA-A receptor modulator.

This is mechanistic research describing how compounds behave in the body. It describes pathways, not outcomes, and it is not a claim that this product treats any condition.

• Vegan · 10 gummies per pouch
• Kanna's serotonergic activity means it should not be combined with SSRIs, SNRIs, MAOIs, or other serotonergic medications. This matters — please talk to your prescriber first.
• Consult your practitioner if pregnant, nursing, or taking any medication

25 mg of Sceletium tortuosum, plus 10 mg valerian root extract.

Not without speaking to your prescriber. Kanna acts on serotonin reuptake, and combining serotonergic agents carries real risk.

Rose and pomegranate — floral and tart rather than sweet.

Sceletium tortuosum is native to South Africa, which is where ours is sourced.

The valerian is a low dose at 10 mg. Most people describe Heart as settling rather than sedating, but individual response varies.

Yes. No gelatin.

• How to use kanna, rose & valerian gummies
• Opening the heart with kanna
• Becoming indigenous